学術論文 (査読審査あり)
野島 高彦
更新: 2023-08-04

  1. Polymerase chain reaction-based biomolecular logic gate for NAND and NOR operations
    Takahiko Nojima*
    Chemistry Letters, Vol. 52, No. 8, August 2023, pp. 647-649.
    DOI: 10.1246/cl.230222

  2. Application of cell-free expression of GFP for evaluation of microsystems
    Takahiko Nojima*, Shohei Kaneda, Hiroshi Kimura, Takatoki Yamamoto and Teruo Fujii
    Frontiers in Bioscience, Vol. 17, January 2012, pp. 1931-1939
    DOI: 10.2741/4029

  3. Modification of the glass surface property in PDMS-glass hybrid microfluidic devices
    Shohei Kaneda, Koichi Ono, Tatsuhiro Fukuba, Takahiko Nojima, Takatoki Yamamoto and Teruo Fujii
    Analytical Sciences, Vol. 28, No. 1, January 2012, pp. 39-44
    DOI:10.2116/analsci.28.39

  4. A rapid method for optimizing running temperature of electrophoresis through repetitive on-chip CE operations
    Shohei Kaneda, Koichi Ono, Tatsuhiro Fukuba, Takahiko Nojima, Takatoki Yamamoto and Teruo Fujii
    International Journal of Molecular Sciences, Vol. 12, No. 7, July 2011, pp. 4271-4281
    DOI:10.3390/ijms12074271
    Vertical News Electronicsで紹介された．[Link]

  5. Pneumatic handling of droplets on-demand on a microfluidic device for seamless processing of reaction and electrophoretic separation
    Shohei Kaneda, Koichi Ono, Tatsuhiro Fukuba, Takahiko Nojima, Takatoki Yamamoto and Teruo Fujii
    Electrophoresis, Vol. 31, No. 22, November 2010, pp. 3719-3726
    DOI:10.1002/elps.201000295
    PMID: 20972987

  6. Millisecond denaturation dynamics of fluorescent proteins revealed by femtoliter container on micro-thermodevice
    Hideyuki F. Arata, Frederic Gillot, Takahiko Nojima, Teruo Fujii and Hiroyuki Fujita
    Lab on a Chip, Vol. 8, No. 9, August 2008, pp. 1436-1440
    DOI:10.1039/b806749j
    PMID: 18818796

  7. selected as a hot articlePolymerase chain reaction-based molecular logic gate coupled with cell-free transcription-translation as a reporter
    Takahiko Nojima*, Takatoki Yamamoto, Hiroshi Kimura and Teruo Fujii
    Chemical Communications, No. 32, June 2008, pp. 3771-3773
    DOI:10.1039/b807039c
    PMID:18685772
    Chemical Science紙の2008年8月号一面で紹介された [Link]
    Chemical Biology Research Article virtual journal, issue 9, 2008 掲載論文に選定された

  8. Cell-free protein synthesis conducted by template DNA with repetitive sequence
    Takahiko Nojima*, Hiroshi Kimura and Teruo Fujii
    Chemistry Letters, Vol. 37, No. 6, June 2008, pp. 648-649
    DOI:10.1246/cl.2008.648

  9. selected as a hot articleEvaluation of cell-free protein synthesis using PDMS-based microreactor arrays
    Takatoki Yamamoto, Mami Hino, Rei Kakuhata, Takahiko Nojima, Yasuo Shinohara, Yoshinobu Baba and Teruo Fujii
    Analytical Sciences, Vol. 24, No. 2, February 2008, pp. 243-246
    DOI:10.2116/analsci.24.243
    PMID:18270416
    論文掲載号における注目論文に選定された (全22論文から3件)

  10. On-chip capillary electrophoresis fractionation of DNA construct for cell-free protein expression
    Takahiko Nojima*, Shohei Kaneda and Teruo Fujii
    Chemistry Letters, Vol. 36, No. 11, November 2007, pp. 1346-1347
    DOI:10.1246/cl.2007.1346

  11. Reactivity ferrocenylcarbodiimide with DNA duplex containing single-mismatched base pairs
    Kosuke Mukumoto, Sadayoshi Watanabe, Takahiko Nojima, Michinori Waki and Shigeori Takenaka
    Analytical Sciences, Vol. 23, No. 7, June 2007, pp. 645-649
    DOI:10.2116/analsci.23.645
    PMID:17575345
    論文掲載号における注目論文に選定された (全23論文から2件)

  12. Analytical ScienceDetection of cRNA hybridized on a DNA chip using tetrakis-acridinyl peptide cassette, consisting of TAP and partial self-complementary oligonucleotide, d[A18(TA)51]
    Katsunori Kawaai, Yasumitsu Kondoh, Takahiko Nojima, Kazuoki Tada, Shigeori Takenaka, Hideo Tashiro and Tomoko Tashiro
    Analytical Sciences, Vol. 23, No. 3, March 2007, pp. 267-pp. 270
    DOI:10.2116/analsci.23.267
    PMID:17372366
    論文誌表紙に選定された (全24論文から1件)

  13. Direct modification of mRNA by ferrocenyl carbodiimide and its application to electrochemical detection of mRNA
    Kosuke Mukumoto, Takahiko Nojima, Shinobu Sato, Michinori Waki and Shigeori Takenaka
    Analytical Sciences, Vol. 23, No. 1, January 2007, pp. 115-119
    DOI:10.2116/analsci.23.115
    PMID:17213635

  14. Fluorescence energy transfer probes based on the guanine quadruplex formation for the fluorometric detection of the potassium ion
    Satoru Nagatoishi, Takahiko Nojima, Elzbieta Galezowska, Bernard Juskowiak and Shigeori Takenaka
    Analytica Chimica Acta, Vol. 581, No. 1, January 2007, pp. 125-131
    DOI:10.1016/j.aca.2006.08.010
    PMID:17386435

  15. G quadruplex-based FRET probes with the thrombin-binding aptamer (TBA) sequence designed for the efficient fluorometric detection of potassium ion
    Satoru Nagatoishi, Takahiko Nojima, Elzbieta Galezowska, Bernard Juskowiak and Shigeori Takenaka
    ChemBioChem, Vol. 7, No. 11, September 2006, pp. 1730-1737
    DOI:10.1002/cbic.200600179
    PMID:17009271

  16. Tetrakis-acridinyl peptide: Distance dependence of photoinduced electron transfer in deoxyribonucleic acid assembles
    Keiji Mizuki, Takahiko Nojima, Bernard Juskowiak and Shigeori Takenaka
    Analytica Chimica Acta, Vol. 578, No. 1, September 2006, pp. 88-92
    DOI:10.1016/j.aca.2006.05.045
    PMID:17723698

  17. Ferrocenylnaphthalene diimide-based electrochemical detection of methylated gene
    Shinobu Sato, Hiroki Kondo, Koji Hokazono, Tastuya Irie, Takashi Ueki, Michinori Waki, Takahiko Nojima and Shigeori Takenaka
    Analytica Chimica Acta, Vol. 578, No. 1, September 2006, pp. 82-87
    DOI:10.1016/j.aca.2006.04.056
    PMID:17723697

  18. Preparation of carbodiimide-terminated dithiolane self-assembly monolayers as a new DNA-immobilization method
    Kosuke Mukumoto, Keiichi Ohtsuka, Takahiko Nojima and Shigeori Takenaka
    Analytical Sciences, Vol. 22, No. 3, March 2006, pp. 349-355
    DOI:10.2116/analsci.22.349
    PMID:16733303

  19. Analysis of electrochemical reaction of ferrocenylnaphthalene diimide captured by double-stranded DNA during the electrochemical detection of DNA hybridization
    Masaharu Komatsu, Takahiko Nojima and Shigeori Takenaka
    Electrochemistry, Vol. 74, No. 1, January 2006, pp. 65-67
    [Abstract]

  20. Immobilization of RNase S-peptide on a single-stranded DNA-fixed gold surface and effective masking of its surface by an acridinyl poly(ethylene glycol)
    Keiichi Ohtsuka, Keiko Uemura, Takahiko Nojima, Michinori Waki and Shigeori Takenaka
    Analyst, Vol. 131, No. 1, January 2006, pp. 55-61
    DOI:10.1039/b508166a
    PMID:16365663

  21. Determination of the termination efficiency of the transcription terminator using different fluorescent profile in green fluorescent protein mutants
    Takahiko Nojima*, Angela C. Lin, Teruo Fujii, and Isao Endo
    Analytical Sciences, Vol. 21, No. 12, December 2005, pp. 1479-1481
    DOI:10.2116/analsci.21.1479
    PMID:16379390

  22. Genotyping of human lipoprotein lipase gene by ferrocenylnaphthalene diimide-based electrochemical hybridization assay
    Takahiko Nojima, Kenichi Yamashita, Atsuko Takagi, Yasuyuki Ikeda, Hiroki Kondo and Shigeori Takenaka
    Analytical Sciences, Vol. 21, No. 12, December 2005, pp. 1437-1441
    DOI:10.2116/analsci.21.1437
    PMID:16379382

  23. Electrochemical telomerase assay with ferrocenylnaphthalene diimide as a tetraplex DNA-specific binder
    Shinobu Sato, Takahiko Nojima and Shigeori Takenaka
    Analytical Chemistry, Vol. 77, No. 22, November 2005, pp. 7304-7309
    DOI:10.1021/ac0510235
    PMID:16285679

  24. Synthesis of ferrocenylcarbodiimide as a convenient electrochemically active labeling reagent for nucleic acids
    Kosuke Mukumoto, Takahiko Nojima and Shigeori Takenaka
    Tetrahedron, Vol. 61, No. 49, November 2005, pp. 11705-11715
    DOI:10.1016/j.tet.2005.09.033

  25. A Pyrene-labeled G-quadruplex oligonucleotide as a fluorescent probe for potassium ion detection in biological applications
    Satoru Nagatoishi, Takahiko Nojima, Bernard Juskowiak and Shigeori Takenaka
    Angewandte Chemie International Edition, Vol. 44, No. 32, July 2005, pp. 5067-5070
    DOI:10.1002/anie.200501506
    PMID:16035025

  26. Supramolecular assembly of fullerene derivatives in the absence or presence of double stranded DNA in water
    Takahiko Nojima, Kenichi Yamashita, Taizo Hatta, Otohiko Tsuge, Toshio Iwase, Naoko Makita, Kenichi Yoshikawa, Satoshi Fujii and Shigeori Takenaka
    Bunseki Kagaku, Vol. 54, No. 6, June 2005, pp. 449-454
    DOI:10.2116/bunsekikagaku.54.449

  27. Supramolecular complex formation by beta-cyclodextrin and ferrocenylnaphthalene diimide-intercalated double stranded DNA and improved electrochemical gene detection
    Shinobu Sato, Takahiko Nojima, Michinori Waki and Shigeori Takenaka
    Molecules, Vol. 10, No. 6, June 2005, pp. 693-707
    DOI:10.3390/10060693
    PMID:18007339
    [PDF (397 kb)]

  28. Fluorescence enhancement of bis-acridine orange peptide, BAO, upon binding to double stranded DNA
    Keiji Mizuki, Yutaka Sakakibara, Hiroyuki Ueyama, Takahiko Nojima, Michinori Waki and Shigeori Takenaka
    Organic & Biomolecular Chemistry, Vol. 3, No. 4, April 2005, pp. 578-580
    DOI:10.1039/b417391k
    PMID:15703790

  29. Interaction analysis of the carcinoembryonic antigen (CEA) with its monoclonal antibody immobilized on a gold surface using Fourier transform infrared reflection-absorption spectroscopy (FT-IR RAS)
    Keiichi Ohtsuka, Masahide Kuroki, Takahiko Nojima, Michinori Waki and Shigeori Takenaka
    Analytical Sciences, Vol. 21, No. 3, March 2005, pp. 215-218
    DOI:10.2116/analsci.21.215
    PMID:15790101

  30. Gene detection based on the tetrakis-acridinyl peptide (TAP) cassette
    Keiji Mizuki, Takahiko Nojima and Shigeori Takenaka
    Chemistry Letters, Vol. 33, No. 12, December 2004, pp. 1550-1551
    DOI:10.1246/cl.2004.1550

  31. J. Organometall. Chem.Electrochemical gene detection based on supramolecular complex formation by ferrocenyl-beta-cyclodextrin and adamantylnaphthalene diimide bound to double stranded DNA
    Shinobu Sato, Takahiko Nojima and Shigeori Takenaka
    Journal of Organometallic Chemistry, Vol. 689, No. 25, December 2004, pp. 4722-4728
    DOI:10.1016/j.jorganchem.2004.08.039
    PMID:15457315
    論文誌表紙に選定された (全26論文から1件)

  32. Immobilization of sunflower trypsin inhibitor (SFTI-1) peptide onto a gold surface and analysis of the interaction with trypsin
    Keiichi Ohtsuka, Ryo Kajiki, Michinori Waki, Takahiko Nojima and Shigeori Takenaka
    Analyst, Vol. 129, No. 10, October 2004, pp. 888-889
    DOI:10.1039/b409178g
    PMID:15457316

  33. Bis-intercalation-triggered fluorescence: Specific detection of double stranded DNA and AT content estimation
    Hiroyuki Ueyama, Keiji Mizuki, Takahiko Nojima and Shigeori Takenaka
    Analyst, Vol. 129, No. 10, October 2004, pp. 886-887
    DOI:10.1039/b410291f
    PMID:15457315

  34. In vitro selection of RNA aptamers that bind to colicin E3 and structually resemble the decoding site of 16S ribosomal RNA
    Ichiro Hirao, Yoko Harada, Takahiko Nojima, Yutaka Osawa, Haruhiko Masaki and Shigeyuki Yokoyama
    Biochemistry, Vol. 43, No. 11, March 2004, pp. 3214-3221
    DOI:10.1021/bi0356146
    PMID:15023071

  35. Comparison of potassium ion preference of potassium sensing oligonucleotides, PSO-1 and PSO-2, carrying human and Oxytricha telomeric sequence, respectively
    Shigeori Takenaka, Hiroyuki Ueyama, Takahiko Nojima and Makoto Takagi
    Analytical and Bioanalytical Chemistry, Vol. 375, No. 8, April 2003, pp. 1006-1010
    DOI:10.1007/s00216-003-1799-z
    PMID:12733011

  36. Direct detection of single nucleotide polymorphism (SNP) with genomic DNA by the ferrocenylnaphthalene diimide-based electrochemical hybridization assay (FND-EHA)
    Takahiko Nojima, Kenichi Yamashita, Makoto Takagi, Atsuko Takagi, Yasuyuki Ikeda, Hiroki Kondo and Shigeori Takenaka
    Analytical Sciences, Vol. 19, No. 1, January 2003, pp. 79-83
    DOI:10.2116/analsci.19.79
    PMID:12558028

  37. PDMS-glass hybrid microreactor array with embedded temperature control device. Application to cell-free protein synthesis
    Takatoki Yamamoto, TeruoFujii and Takahiko Nojima
    Lab on a Chip, Vol. 2, No. 4, November 2002, pp. 197-202
    DOI:10.1039/b205010b
    PMID:15100810

  38. Synthesis of DNA templates containing the fifth base, 2-amino-6-(dimethylamino)purine, for specific transcription involving unnatural base pairs
    Ichiro Hirao, Takahiko Nojima, Tsuneo Mitsui and Shigeyuki Yokoyama
    Chemistry Letters, Vol. 30, No. 9, September 2001, pp. 914-915
    DOI:10.1246/cl.2001.914

  39. Development of hybrid microreactor for protein synthesis
    Takatoki Yamamoto, Teruo Fujii, Takahiko Nojima, Jong Wook Hong and Isao Endo
    Transactions of the Institute of Electrical Engineers of Japan, Vol. 121E, No. 4, April 2001, pp. 163-168

  40. Microbiochemical reactors for enzymatic reactions including cell-free mRNA translation
    Kazuo Hosokawa, Teruo Fujii, Takahiko Nojima, Shuichi Shoji, Akira Yotsumoto and Isao Endo
    Journal of Micromechatronics, Vol. 1, No. 1, January 2000, pp. 85-98
    DOI:10.1163/156856300744687

  41. Cell-free protein synthesis in a microfabricated reactor
    Takahiko Nojima*, Teruo Fujii, Kazuo Hosokawa, Akira Yotsumoto, Shuichi Shoji and Isao Endo
    Bioprocess Engineering, Vol. 22, No. 1, January 2000, pp. 13-17
    DOI:10.1007/PL00009093

  42. How amino acids control the binding of Cu(II) ions to DNA (I). The role of hydroxyl group of serine and threonine in fixing the orientation of the complexes
    Wataru Harada, Takahiko Nojima, Akinori Shibayama, Hiroyuki Ueda, Heisaburo Shindo and Makoto Chikira
    Journal of Inorganic Biochemistry, Vol. 64, No. 4, December 1996, pp. 273-285
    DOI:10.1016/S0162-0134(96)00061-X

  43. Pyridine-promoted factor- and energy-free peptide synthesis systems prepared from various organisms including prokaryote, eukaryote, and mitochondria
    Takahiko Nojima, Itaru Nitta, Takuya Ueda and Kimitsuna Watanabe
    Journal of Biochemistry, Vol. 119, No. 6, June 1996, pp. 1076-1079
    PMID:8827440

  44. A novel factor- and energy-free translation system promoted by tertiary amines and its implications toward the origine of life
    Itaru Nitta, Takuya Ueda, Takahiko Nojima and Kimitsuna Watanabe
    Viva Origino, Vol. 23, December 1995, pp. 209-222

  45. Template-dependent polypeptide synthesis in a factor- and energy-free translation system promoted by pyridine
    Itaru Nitta, Takuya Ueda, Takahiko Nojima and Kimitsuna Watanabe
    Journal of Biochemistry, Vol. 118, No. 4, October 1995, pp. 841-849
    PMID:8576102

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